Which medication is not listed as an intranasal option in the material?

• A. Cefazolin
• B. Narcan
• C. Midazolam
• D. Ketamine

Answer: (A)

The point here is recognizing which drugs have viable intranasal formulations for rapid, needleless delivery in the field. In the material, medications listed for intranasal use include naloxone (Narcan) for opioid overdose, midazolam for seizures or sedation, and ketamine for analgesia or sedation. These drugs have reliable nasal absorption and established nasal formulations, making the intranasal route practical in prehospital care.

Cefazolin, a cephalosporin antibiotic, is normally given by IV or IM and does not have a standard, effective intranasal formulation for acute use. Its absorption through the nasal mucosa is not reliable for clinical purposes in this setting, so it isn’t listed as an intranasal option.

That’s why cefazolin is the correct choice as not being listed for intranasal administration.